When you are looking for your ancestors on the census, make notes of who is living nearby. It never hurts to note who is living nearby so that when you can't find your ancestors because of bad indexing or other reasons, you can search for the nearby neighbors and perhaps that will lead you back to your family. Pay close attention to unusual names. At times searching for them can be easier than searching for John or Elizabeth!
Hopefully the neighbors didn't move back to Missouri!